I have tried different settings inside of DOpus to set it to only one instance at a time. However, when I double click on "My Computer", a new instance of DOpus opens up.
Is there a way to force all files/folders to open up in one instance of DOpus?
Sorry, I just found the answer. The answer is here:
[Always re-use a single window instead of opening new windows)
PS> Thanks again Leo 