Opus doesn't launch at startup

Opus 12.7 on Win 10 64-bit

Inside Opus I've selected the start with windows option.
Opus show in the Startup folder as Directory Opus (Startup)
Opus just doesn't start. It's not on my taskbar, tray or in taskmanager.
Opus has full permissions Shows ADMINSTRATOR in top left of every lister.

It simply doesn't start. It did start on the same Win 10 before I was forced to reinstall because my HDD died.
Maybe Windows and/or Opus is newer due to updates.

Any help to get me back on track is much appreciated.

Best wishes for 2018

That could be what is blocking it from running at startup, and generally a bad idea. This page explains why in detail: