I encounter this issue from time to time where the columns don't line up with the column header in details mode.
Examine the screenshot below.
This is the same as your DO12 - Column Headers offset issue thread.
It's caused by a combination of very narrow columns (you're using random "sacrificial" columns set to 4 pixels wide to make them look like borders around other columns), and using multi-sort mode which has to add extra sort buttons to the left of the column header.
If those sort buttons are thinner than the first column, the problem occurs. We spent some time looking at it but it's extremely difficult to fix, and not something likely to happen under normal use.
If you remove that first 4 pixel Full Path column, the problem will stop.
You'll probably also find things speed up if you remove the 4 pixel Duration column as it has to open and parse every media file in the folder to populate its information which you aren't really showing. (If you want some dummy columns to use as 4 pixel borders between other columns, making a simple script add-in that adds 5 columns that don't display anything might be a good idea. Then you can use those columns instead of random built-in ones.)
Thanks Leo, I removed the 'duration column' to minimize unnecessary calculations, good tip.
The columns aren't actually 'sacrificial', I sometimes sort by these thin columns (like file extension) but I don't need to actually 'see' the column since I can discern the extension in the filename in that instance.
I read that you can group by columns that aren't visible which is cool but I haven't tried that yet.
Thanks again, bless