The minidump indicates you're seeing it with Opus 12.20, so that probably isn't what changed (unless you only updated to it recently).
According to the minidump, the crash is due to a thread running out of stack, which probably means something is stuck in a recursive loop. The code running when this happened is part of python38.dll, not Opus.
I can't see much else since I don't have debug symbols for python38.dll, but with a stack overflow it's likely to be a bug within that code/DLL, calling itself over and over.
Python is up to date, but not new (3.8.3+pywin227). This started after I began to "try things" in some of my code, so it's probable that I am triggering some side effect I am not aware of.
Thanks, that gives me a point to start.