After some time copying and moving files from one Dopus windows to another, the content take longuer and longer to get refreshed. Easily more than one minute after half an hour of files manipulations. However, a "hard refresh" with F5 works fine. What about that?
Please see Changes to folders are not always detected for suggestions. A log of the debug output is needed if none of the other suggestions solve it.
Parts of Crash, exit or high CPU when viewing certain directories may also be relevant, for example of a cloud storage shell extension is responsible for the slowdown. Using ShellExView to disable non-Microsoft shell extension may be worth a try.