DO suddenly slow on 1st run after installing PDF-XChange

I think the only one you need to disable is the Column Handler, which won't affect the Preview Handler. It's this one if you're using ShellExView:

2021-04-26 17-37-40 Clipboard Image

Alternatively, in Opus, adding {D8716A0E-4E9F-4D3F-BF1B-3460D86BB310} to Preferences / Miscellaneous / Advanced [Troubleshooting]: ignore_context_menus seems to be enough to fix things, at least from my quick testing.

(ignore_context_menus also blocks some non-context menu things these days.)

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