It is that.
If it is on, that toolbars hotkeys are always enabled in listers, even if the toolbar itself is not visible.
Turn it off for any toolbars where you don't want to always enable their keys in listers.
When you go from Opus 9, to 10, to 11, to 12, you get new versions of the default toolbars. Your old versions (if any) are renamed with a number, so they are not lost if you had changes you want to save, or if you want to go back to a completely custom toolbar and ignore the new defaults.
See Your old toolbars are still there after you upgrade in the FAQs.
If you aren't using and don't want those copies of the toolbars, you can delete them.