under Preferences > Layouts and Styles > Layouts, you can choose to either close all existing listers or open a new lister when a different layout is selected. This can be set per layout.
I have several layouts defined, with all of them set to close all existing listers when loading. This is because I only want to ever have a single lister open at any time. Each layout opens in dual pane mode, with a single tab in each pane.
What I would like to be able to do is select a new layout and have that layout open as a new pair of tabs (one per pane), keeping the original tabs as they were. Then, using the tabs groups I could switch between pairs of tabs. I suspect this cannot be achieved without replacing the layout but I thought I'd ask in case it was a possible enhancement.