If a crash dump is produced matching the date/time of the crash, could you zip it and send it to me via private message?
The folder name with random letters suggests that something loaded into the Opus process is corrupting memory within the process, although it's just a guess. It's unlikely (though not impossible) that it's Opus itself, else we'd probably have lots of similar reports, so a more likely scenario is that a shell extension installed by another tool is going wrong and corrupting memory. This is assuming the strange folder name and the crash are related, which seems likely.
You can use ShellExView to see which shell extensions are installed on your system. The Microsoft ones can usually be ignored, and it has an option to filter them out. For any other ones, it may be worth a try to disable them, then shutdown exit Opus (don't just close all its windows, fully exit Opus), and see if the problem goes away. If the crash still happens, if wasn't an extension and you can re-enable them all again. On the other hand, if the crash has gone away, enable half the extensions again and try again, to see which half the problem extension is in. You can then repeat the process to narrow it down to a particular extension.