Something else to try next time it happens (after everything else, as it may mean the problem stops and you have to wait again for it to re-occur):
- Use File > Exit Directory Opus to completely shut-down dopus.exe
- Then restart it and see if the problem is still happening.
That might indicate if it's a condition inside dopus.exe or something outside it. (That won't tell us everything, but it might narrow down the types of things to look for.)
The new dump shows only these components loaded into the process:
C:\ProgramData\Sync.Com DLL\overlay.dll
C:\Users\<username>\AppData\Local\Microsoft\OneDrive\19.174.0902.0013\amd64\FileSyncShell64.dll
That's a much smaller list than before. If you didn't disable all the other things, it might just mean the dump was taken before anything was loaded (e.g. before a window or Edit control was opened and triggered the various extensions and hooks to be loaded).
Windows Defender can potentially cause delays on any file access, so it would need to be disable entirely to test if it's involved.