Several people have recently started experiencing problems in IE, Explorer and Office, as well as with context menus and File Open dialogs (amoung other things) in various applications, including Opus.
These problems are unrelated to the recent Opus 220.127.116.11 update, and unrelated to Opus in general. The actual cause is a conflict between a recent Microsoft security update and other software you may have installed on your system.
Please see this Microsoft bulletin for further information on the problem's cause, symptons and workarounds:
I can confirm that there is no conflict between the security update and Opus itself as I am running the latest Opus and Windows updates on three machines without any problems.