Please help me fix this issue: I had to reinstall windows and when I reinstall Opus, I can not scale these icons (the back, forward, go up arrow) to normal size, they are very tiny! . I have tried different combinations of High DPI compatability settings under properties for the EXE file with no success. Thank you

The DPI compatibility settings are not needed so you should turn them off. Most probably you just need to reboot after changing the system DPI.
Tried this too, no luck. The rest of directory Opus screen (see screenshot) is perfect except for the TINY and almost invisible direction icons (notated in red) They are so small I can hardly use them. My screen is Dell XPS13 UHD 4k resolution. PLEASE somebody help. It was perfect until I (not by choice) I reinstalled windows 10. THANK you to anybody in advance
Those look like a custom icon set.
If you go to Preferences / Toolbars / Icons and move Internal Icon Set to the top of the list, then click Apply, are the icons still small?
Are any other Compatibility Settings turned on for dopus.exe? They should all be off.
Argggh Thanks to all for suggestions but after trying all these solutions, they only slightly enlarge the icons, still nowhere near normal. also, the one icon I can not barely see is the sorting indicator in the lister (see picture)--->
. I wish D Opus could make this simpler for 4k screens like on XPS13 so that a universal setting could be implimented easily and quickly. Before I reinstalled Win10, all of my displays were perfect on D Opus, right out of the box.. very frustrated . thanks to all
It usually is easy, since it just follows the system setting, but something is clearly messing it up.
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In your Display Settings (the one that is part of Windows, not part of Opus), what is the Scale % set to?
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Please also show is a screenshot of the Properties > Compatibility tab for dopus.exe, as well as the Change high DPI Settings dialog which you can get to from that tab.. It looks like Opus thinks it is running on an earlier version of Windows from your screenshots, unless you've gone out of your way to configure things like the gradients.
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Is the Windows icon on your taskbar also tiny? I have seen that happen when the whole OS is confused about DPI, and it's usually solved by logging out and back in again.
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Are you using Remote Desktop or anything else that might complicate the DPI situation?
This is very strange.
To check which DPI Opus thinks it's running in, please open this:
Make sure Script Interpreter is turned on, at the bottom left, and set to JScript.
Paste this code into the top:
DOpus.Output("DPI = " + DOpus.DPI.dpi);
DOpus.Output("Factor = " + DOpus.DPI.factor);
Then push F5 (or click the triangle icon at the bottom) to run the script.
My system is set to 200% so it outputs this in the bottom pane:
DPI = 192
Factor = 200
With yours set to 250%, I'd expect to see:
DPI = 240
Factor = 250
Do you see that, or something else?
Also, are there any other monitors plugged into your system, now or since it was last rebooted?
Is it a laptop with different DPI built-in and external monitors, or a desktop with multiple monitors at different DPIs?
One final (for now) thing to try: Use File > Exit Directory Opus, then re-launch it. Does that change anything?
No external monitors, just the laptop screen. Everything looks fine except for certain icons
The error is because the script mode is set to VBScript. Change it to JScript.
Have you installed Opus 11 on this machine by mistake? 
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