UI scaling with multiple resolution displays

Hello all,
I am currently working on a dual monitor setup of different resolutions and windows scaling.
A 32" 4K display at 150% windows scaling and a 42" HD display at 100% windows scaling, on top.
Applications such as Mozilla FF & TB, the Adobe apps and File Explorer,
all will scale accordingly showing crisp text on each display and the right size of UI.

Opus (12.21) will scale nicely on the 4K display, but on the HD display although text is still sharp and not blurry, it is as if still in 150% mode.
Everything is large, tabs, fonts, toolbars etc.
I have tried various options in the compatibility tab for the program, but none seem to work as other applications do by default.

Any solution?
Thank you

Opus is DPI aware and scales to the system DPI, but isn't multi-monitor DPI aware.

Per-monitor DPI support is a much larger and more complex task, and also hindered by the issue that the OS itself is horrible to use and still full of bugs in that mode, which makes us reluctant to use it ourselves for development and testing (and makes spending time on it feel futile, because it's still a miserable experience, whatever we do).

same setup - i get round it by scaling both to 125% - not the best of solutions but works for me.