Unable to uninstall DOpus 12

The uninstaller would depend on other registry/filesystem data which are probably also missing if it's not appearing in the Program and Features list.

It might be worth checking Problems installing Opus and deleting the Installshield Installation Information folder mentioned in the last part.

Aside from that, I am pretty much at a loss. If the Windows install is messed up then it could be very hard to work out what is going wrong.