WinXP File Indexing

Does setting WinXP drive, directory and file indexing services (or individual drives) to OFF have any effect on Dopus?
I have tried both on and off and can see no major difference. Supposedly removing indexing speeds up WinXP generally -- that does seem to be the case.
I am wondering about Dopus though.

Using latest version 8


As far as I know, Opus doesn't take advantage of the indexing service so if you turn it off it won't affect Opus.

(I've turned mine off.)