Directory Opus doesn't capture usb disk. It's annoying to use Explorer and Opus at the same time

What do you mean by 'capture'?

When I insert a pendrive the autoplay launches an explorer window. I'd like that Opus is opened instead of explorer

What are the Windows autoplay settings configured to do on your system?

Here are mine on Windows 10, where inserting a USB stick causes an Opus window to open: