Testing conversion of that image to PNG in Opus and MSPaint showed it was a lot slower in Opus, but also a lot better compressed in the end.
So it might be that the compression mode we're using is really taxing on large images. I've made a note to look into it when we have time. Speeding this up would be nice, while keeping the option for max compression if people need that more (assuming that's what's making it slow).