Actually it does not exactly crash. The first PDF file selected in a lister is previewed correctly by the PDFXchange Preview Handler. But then, docsvw64.exe seems to hang since after selecting another file in the lister (PDF or any other file), the preview pane stays empty.
Then, Dopus has to be killed via Task Manager. After a restart of Dopus, the same problem starts all over again -- only with a second (third... etc.) instance of docsvw64.exe.
It might be worth rebooting, if you haven't tried that already, in case a component of the viewer is in a stuck state from the previous attempts. But if it still doesn't work in Explorer, definitely worth talking to Tracker to get that resolved first as it indicates something wrong with the viewer in general.