DOpus (x64 USB version) can't create or open Zip files

Config backups get zipped so if zipping isn't working the backup wizard won't work either.

The config is all stored in files -- no registry settings -- so you can back it up by hand if needed (see here).

Opus 9 64-bit uses a COM object/exe for zip support. If you have something blocking the exe (dopusx64.exe) or the main Opus process from talking to it (e.g. anti-virus/firewall or similar set to a very paranoid mode) then that could be what's going wrong.