My DOpus crashes when I move the mouse on it

  1. Did you install your certificate? One idea, but maybe just the trial license expired and the fact that the license manager is displayed is off-putting for some reason to a poor designed antivirus. Doesn't hurt to try install your certificate from command line.
  2. If you used a pirated version, and copied some files somewhere, probably that's the cause. I doubt about some registry entries.