You might be able to do it all with a single very complex regular expression, but I don't think it'd be a good way to do things.
Easier, if you want to do things all in one go, would be to use a rename script which can apply a regular expression and then a search & replace (or a second regular expression) one after the other. Script to perform multiple Regular Expressions has an example.
Alternatively, if you don't mind doing things in two steps, set up one rename preset to do the rename above, and a second to replace the dots with spaces. Dots to spaces except in numbers is good for that, and avoids breaking things like "v1.2" version numbers.