Right click on any drive icon within Directory Opus causes file manager to freeze.
That is usually caused by bad shell extensions installed by drive partitioning, imaging or defrag tools. (e.g. The "Alcohol" tool has caused problems for lots of people. If you have that installed, it's probably the cause and disabling its shell extension will likely fix things.)
More detail in this recent thread:
Thanks so much! Alcohol was the culprit.