Since DO10 first start took very long

Try some of the things in this FAQ to see if you can narrow down what is causing the slow start:

Backing up your configuration, then resetting to a default config may also be worth a try. If it's still slow even then, you could try going back to Opus 9 (also with a default config) to prove that changing Opus versions was actually the difference (it's possible but it is almost never the actual cause).