From a quick look, they're still valid.
That depends what you want to clear.
You can see there are lots of other config files in the config folders. Almost all are in text/xml format so you can open them in Notepad to see the kind of data they contain and if you'd like to clear it. Or if there's a particular thing you want to clear (e.g. the name of a folder) you could do a contents search to find all config files containing that item.
Everything under the /dopuslocaldata folder is non-essential and can be deleted if you wish. You may lose window positions or remembered checkbox states in some dialogs for doing things, but not any actual Preferences settings.
Under the /dopusdata folder are things that are typically saved explicitly, rather than implicitly, but there may still be things there you want to clear out at some point. Most of them can be managed via the Preferences UI or similar, however, so you would not normally need to edit/delete most of the things in there by hand.
These guides talk more about the config folders and the files within them:
- How to backup or locate your Opus configuration (Simple)
- How to backup or locate your Opus configuration (Advanced)
It contains recently visited folders. It can be deleted if you want to clear those.
You can also turn off the recent list under Preferences / Favorites and Recent / Recent List to stop them being saved.
Edit 2024: For people finding this thread, Opus 13 has Preferences / Miscellaneous / Privacy.